An efficient, concise, and scalable synthesis of Izenamide A and B via asymmetric reduction of γ-amino β-keto ester using 2-methyl-CBS-oxazaborolidine catalysts
A efficient and concise synthesis of izenamides A and B is reported. We have followed a more convergent approach while avoiding costly and harmful chemicals. Major attraction of this synthesis is the first ever report of highly asymmetric reduction of N-Boc γ-amino β-ketoester using 2-Methyl-CBS-oxa...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-01-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715622004751 |