Mechanisms of initiation of cortical spreading depression

Abstract Background There is increasing evidence from human and animal studies that cortical spreading depression (CSD) is the neurophysiological correlate of migraine aura and a trigger of migraine pain mechanisms. The mechanisms of initiation of CSD in the brain of migraineurs remain unknown, and...

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Bibliographic Details
Main Authors: Marina Vitale, Angelita Tottene, Maral Zarin Zadeh, KC Brennan, Daniela Pietrobon
Format: Article
Language:English
Published: BMC 2023-08-01
Series:The Journal of Headache and Pain
Subjects:
Online Access:https://doi.org/10.1186/s10194-023-01643-9