Activated Natural Killer Cell Inoculation Alleviates Fibrotic Liver Pathology in a Carbon Tetrachloride-Induced Liver Cirrhosis Mouse Model

Activated Natural Killer Cell Inoculation Alleviates Fibrotic Liver Pathology in a Carbon Tetrachloride-Induced Liver Cirrhosis Mouse Model

Activated hepatic stellate cells (HSCs) play a detrimental role in liver fibrosis progression. Natural killer (NK) cells are known to selectively recognize abnormal or transformed cells via their receptor activation and induce target cell apoptosis and, therefore, can be used as a potential therapeu...

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Bibliographic Details
Main Authors: Ho Rim Oh, Min Kyung Ko, Daehee Son, Young Wook Ki, Shin-Il Kim, Seok-Yong Lee, Keon Wook Kang, Gi Jeong Cheon, Do Won Hwang, Hyewon Youn
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomedicines
Subjects:
liver cirrhosis
carbon tetrachloride (CCl<sub>4</sub>)
natural killer (NK) cells
bioluminescence imaging (BLI)
Online Access:https://www.mdpi.com/2227-9059/11/4/1090

Internet

https://www.mdpi.com/2227-9059/11/4/1090

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