Immortalization effect of SV40T lentiviral vectors on canine corneal epithelial cells

Immortalization effect of SV40T lentiviral vectors on canine corneal epithelial cells

Abstract Background Primary canine corneal epithelial cells (CCECs) easily become senescent, and cell proliferation is limited. Therefore, sampling for experimentation requires a large number of animals, which is problematic in terms of animal welfare and fails to maintain the stability of the cells...

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Bibliographic Details
Main Authors: Long Guo, Zhihao Wang, Jun Li, Jianji Li, Luying Cui, Junsheng Dong, Xia Meng, Chen Qian, Heng Wang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Veterinary Research
Subjects:
Canine
Corneal epithelial cell
SV40T
Immortalization
Staphylococcus pseudintermedius
Inflammation
Online Access:https://doi.org/10.1186/s12917-022-03288-3

Internet

https://doi.org/10.1186/s12917-022-03288-3

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