Immortalization effect of SV40T lentiviral vectors on canine corneal epithelial cells
Abstract Background Primary canine corneal epithelial cells (CCECs) easily become senescent, and cell proliferation is limited. Therefore, sampling for experimentation requires a large number of animals, which is problematic in terms of animal welfare and fails to maintain the stability of the cells...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-05-01
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Series: | BMC Veterinary Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12917-022-03288-3 |