Epidermal growth factor receptors siRNA-conjugated collagen modified gold nanoparticles for targeted imaging and therapy of lung cancer

Epidermal growth factor receptors siRNA-conjugated collagen modified gold nanoparticles for targeted imaging and therapy of lung cancer

Epidermal growth factor receptor (EGFR), a critical factor promotes lung cancer cell proliferation and survival. Knockdown of EGFR expression thus promise beating lung cancer clinically. Functionalized gold nanoparticles may serve an effective vehicle carrying theranostic bio-active materials. Herei...

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Bibliographic Details
Main Authors: Alex Yang-Hao Yu, Ru-Huei Fu, Shan-hui Hsu, Chen-Feng Chiu, Wei-Hsiang Fang, Chun-An Yeh, Cheng-Ming Tang, Hsien-Hsu Hsieh, Huey-Shan Hung
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Materials Today Advances
Subjects:
Epidermal growth factor receptor
Gold nanoparticle (AuNP)
Small-interfering RNA (siRNA)
Lung cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2590049821000618

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http://www.sciencedirect.com/science/article/pii/S2590049821000618

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