Natural polymorphisms in the resistance associated sites of HCV-G1 NS5B domain and correlation with geographic origin of HCV isolates

Natural polymorphisms in the resistance associated sites of HCV-G1 NS5B domain and correlation with geographic origin of HCV isolates

Abstract Background We evaluated the frequency of naturally occurring resistance associated substitutions (RASs) and their characteristic of polymorphic or non-polymorphic amino acid change to direct acting antivirals (DAAs) in NS5b HCV subtypes 1a and 1b according to different geographic origin of...

Full description

Bibliographic Details
Main Authors: Sabrina Bagaglio, Caterina Uberti-Foppa, Alessandro Olgiati, Emanuela Messina, Hamid Hasson, Camilla Ferri, Giulia Morsica
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Virology Journal
Subjects:
Anti-HCV direct acting antivirals (DAAs)
Geographic distribution
HCV genotype
NS5b polymerase inhibitors
Resistance associated substitutions (RASs)
Online Access:http://link.springer.com/article/10.1186/s12985-018-1054-z

Internet

http://link.springer.com/article/10.1186/s12985-018-1054-z

Similar Items