Bone protein “extractomics”: comparing the efficiency of bone protein extractions of Gallus gallus in tandem mass spectrometry, with an eye towards paleoproteomics

Proteomic studies of bone require specialized extraction protocols to demineralize and solubilize proteins from within the bone matrix. Although various protocols exist for bone protein recovery, little is known about how discrete steps in each protocol affect the subset of the bone proteome recover...

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Bibliographic Details
Main Authors: Elena R. Schroeter, Caroline J. DeHart, Mary H. Schweitzer, Paul M. Thomas, Neil L. Kelleher
Format: Article
Language:English
Published: PeerJ Inc. 2016-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/2603.pdf