Overexpression of transcription factor Sp1 leads to gene expression perturbations and cell cycle inhibition.
BACKGROUND:The ubiquitous transcription factor Sp1 regulates the expression of a vast number of genes involved in many cellular functions ranging from differentiation to proliferation and apoptosis. Sp1 expression levels show a dramatic increase during transformation and this could play a critical r...
Asıl Yazarlar: | , , , , , , , , , , , , , , |
---|---|
Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
Public Library of Science (PLoS)
2009-09-01
|
Seri Bilgileri: | PLoS ONE |
Online Erişim: | http://europepmc.org/articles/PMC2737146?pdf=render |