Examining Neurosteroid-Analogue Therapy in the Preterm Neonate For Promoting Hippocampal Neurodevelopment

Examining Neurosteroid-Analogue Therapy in the Preterm Neonate For Promoting Hippocampal Neurodevelopment

Background: Preterm birth can lead to brain injury and currently there are no targeted therapies to promote postnatal brain development and protect these vulnerable neonates. We have previously shown that the neurosteroid-analogue ganaxolone promotes white matter development and improves behavioural...

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Bibliographic Details
Main Authors: Julia C. Shaw, Rebecca M. Dyson, Hannah K. Palliser, Ryan P. Sixtus, Heather Barnes, Carlton L. Pavy, Gabrielle K. Crombie, Mary J. Berry, Jonathan J. Hirst
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Physiology
Subjects:
neurosteroids
preterm neonatal brain
oligodendrocyte
GABA
glutamate
neuron
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.871265/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.871265/full

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