ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1

ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1

Abstract Background ISGylation is a post-translational protein modification that regulates many life activities, including immunomodulation, antiviral responses, and embryo implantation. The exact contribution of ISGylation to folliculogenesis remains largely undefined. Results Here, Isg15 knockout...

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Bibliographic Details
Main Authors: Yaru Chen, Jiawei Zhou, Shang Wu, Lei Wang, Gaogui Chen, Dake Chen, Xianwen Peng, Yi-Liang Miao, Shuqi Mei, Fenge Li
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Cell & Bioscience
Subjects:
Interferon-stimulated gene 15
ISGylation
ADAMTS1
Ovulation
Female fertility
Mice
Online Access:https://doi.org/10.1186/s13578-023-01024-4

Internet

https://doi.org/10.1186/s13578-023-01024-4

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