Biological Significance of YAP/TAZ in Pancreatic Ductal Adenocarcinoma

Biological Significance of YAP/TAZ in Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal types of cancer. Despite major advances in defining the molecular mutations driving PDAC, this disease remains universally lethal with an overall 5-year survival rate of only about 7–8%. Genetic alterations in PDAC are exemplifie...

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Bibliographic Details
Main Authors: Hiromitsu Hayashi, Norio Uemura, Liu Zhao, Kazuki Matsumura, Hiroki Sato, Yuta Shiraishi, Hideo Baba
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
pancreatic cancer
Hippo signaling pathway
Yes-associated protein
TAZ
KRAS mutation
pancreatic ductal adenocarcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.700315/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.700315/full

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