Role of <italic toggle="yes">Toxoplasma gondii</italic> Chloroquine Resistance Transporter in Bradyzoite Viability and Digestive Vacuole Maintenance

Role of <italic toggle="yes">Toxoplasma gondii</italic> Chloroquine Resistance Transporter in Bradyzoite Viability and Digestive Vacuole Maintenance

ABSTRACT Toxoplasma gondii is a ubiquitous pathogen that can cause encephalitis, congenital defects, and ocular disease. T. gondii has also been implicated as a risk factor for mental illness in humans. The parasite persists in the brain as slow-growing bradyzoites contained within intracellular cys...

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Détails bibliographiques
Auteurs principaux: Geetha Kannan, Manlio Di Cristina, Aric J. Schultz, My-Hang Huynh, Fengrong Wang, Tracey L. Schultz, Matteo Lunghi, Isabelle Coppens, Vern B. Carruthers
Format: Article
Langue:English
Publié: American Society for Microbiology 2019-08-01
Collection:mBio
Sujets:
Toxoplasma gondii
autophagy
persistence
proteolysis
transporters
Accès en ligne:https://journals.asm.org/doi/10.1128/mBio.01324-19

Internet

https://journals.asm.org/doi/10.1128/mBio.01324-19

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