Immunoregulatory effect of Lactobacillus paracasei VL8 exopolysaccharide on RAW264.7 cells by NF-κB and MAPK pathways

Immunoregulatory effect of Lactobacillus paracasei VL8 exopolysaccharide on RAW264.7 cells by NF-κB and MAPK pathways

This study explored the immunoregulatory mechanism of VL8-EPS, obtained from Viili. An RAW264.7 macrophage cell-line was used along with real-time quantitative PCR to evaluate the impact of VL8-EPS on mRNA expression of IL-1β, TNF-α, IL-6, IL-10, and TLR4. Moreover, western blot assay was conducted...

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Bibliographic Details
Main Authors: Jie Gao, Qi Li, Yuwei Liu, Bing Yang, Faizan Ahmed Sadiqb, Xiyu Li, Si Mi, Yaxin Sang
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Journal of Functional Foods
Subjects:
Polysaccharide
Lactobacillus paracasei
RAW264.7 cells
Immunomodulatory activity
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622002365

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http://www.sciencedirect.com/science/article/pii/S1756464622002365

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