Crystal structure of the retroviral protease‐like domain of a protozoal DNA damage‐inducible 1 protein

DNA damage‐inducible 1 (Ddi1) is a multidomain protein with one of the domains being retropepsin‐like. HIV‐1 protease inhibitors were found to reduce opportunistic infections caused by pathogens like Leishmania and Plasmodium, and some of them were shown to inhibit the growth of these parasites. In...

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Bibliographic Details
Main Authors: Sushant Kumar, Kaza Suguna
Format: Article
Language:English
Published: Wiley 2018-09-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12491