Comparison of intra-articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint fibrosis in an experimental model of knee arthroplasty

Comparison of intra-articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint fibrosis in an experimental model of knee arthroplasty

Abstract Background Dysregulated inflammatory responses are implicated in the pathogenesis of joint stiffness and arthrofibrosis following total knee arthroplasty (TKA). The purpose of this study was to compare the effects of intra-articular (IA) administration of tranexamic acid (TXA), an anti-fibr...

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Bibliographic Details
Main Authors: Jodie L. Morris, Hayley L. Letson, Peter McEwen, Erik Biros, Constantin Dlaska, Kaushik Hazratwala, Matthew Wilkinson, Geoffrey P. Dobson
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Total knee arthroplasty
Stiffness
Arthrofibrosis
Inflammation
Tranexamic acid
Online Access:https://doi.org/10.1186/s13018-021-02871-y

Internet

https://doi.org/10.1186/s13018-021-02871-y

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