Mutational signature analysis in non-small cell lung cancer patients with a high tumor mutational burden

Mutational signature analysis in non-small cell lung cancer patients with a high tumor mutational burden

Abstract Background Lung cancer is the leading cause of cancer death worldwide. With the growing number of targeted therapies and the introduction of immuno-oncology (IO), personalized medicine has become standard of care in patients with metastatic disease. The development of predictive and prognos...

Full description

Bibliographic Details
Main Authors: Guus R. M. van den Heuvel, Leonie I. Kroeze, Marjolijn J. L. Ligtenberg, Katrien Grünberg, Erik A. M. Jansen, Daniel von Rhein, Richarda M. de Voer, Michel M. van den Heuvel
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Respiratory Research
Subjects:
Mutational signatures
Next generation sequencing
Non-small cell lung cancer
Cancer genetics
Online Access:https://doi.org/10.1186/s12931-021-01871-0

Internet

https://doi.org/10.1186/s12931-021-01871-0

Similar Items