Cyanidin-3-galactoside ameliorates silica-induced pulmonary fibrosis by inhibiting fibroblast differentiation via Nrf2/p38/Akt/NOX4

Cyanidin-3-galactoside ameliorates silica-induced pulmonary fibrosis by inhibiting fibroblast differentiation via Nrf2/p38/Akt/NOX4

Aronia melanocarpa is rich in anthocyanins with many beneficial effects. Cyanidin-3-galactoside (C3G), the most abundant anthocyanin in Aronia melanocarpa was extracted and applied to silica particle-induced (SP-induced) pulmonary fibrosis mice and transforming growth factor-β-induced differentiatio...

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Bibliographic Details
Main Authors: Chuang Ma, Mingyue Lyu, Chilu Deng, Xia Liu, Yanmin Cui, Yixiao Shen, Xianjun Meng, Jin Zhao
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Journal of Functional Foods
Subjects:
Aronia melanocarpa
Cyanidin-3-galactoside
Pulmonary fibrosis
Fibroblast differentiation
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622001049

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http://www.sciencedirect.com/science/article/pii/S1756464622001049

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