Sex differences in methylation profiles are apparent in medulloblastoma, particularly among SHH tumors

Sex differences in methylation profiles are apparent in medulloblastoma, particularly among SHH tumors

BackgroundMedulloblastoma, the most common malignant pediatric brain tumor, displays marked sex differences in prevalence of the four main molecular subgroups: SHH, WNT, Group 3 and Group 4. Males are more frequently diagnosed with SHH, Group 3 and 4 tumors, which have worse prognoses than WNT tumor...

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Bibliographic Details
Main Authors: Rachel M. Moss, Natali Sorajja, Lauren J. Mills, Christopher L. Moertel, Thanh T. Hoang, Logan G. Spector, David A. Largaespada, Lindsay A. Williams
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Oncology
Subjects:
medulloblastoma
sex differences
methylation
survival
pediatric and young adult cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1113121/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1113121/full

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