Reduction of lns-1 gene expression and tissue insulin levels in n5-STZ rats
Objective: The high global incidence of type 2 diabetes has challenged researchers to establish animal models that resemble the chronic stage observed in type 2 diabetes patients. One such model is induced by neonatal streptozotocin (n-STZ) administration to rat pups at 0, 2, or 5 days after birth....
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2013-01-01
|
Series: | Biological Research |
Subjects: | |
Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000300009&lng=en&tlng=en |