Reduction of lns-1 gene expression and tissue insulin levels in n5-STZ rats

Reduction of lns-1 gene expression and tissue insulin levels in n5-STZ rats

Objective: The high global incidence of type 2 diabetes has challenged researchers to establish animal models that resemble the chronic stage observed in type 2 diabetes patients. One such model is induced by neonatal streptozotocin (n-STZ) administration to rat pups at 0, 2, or 5 days after birth....

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Bibliographic Details
Main Authors:	Belinda Vargas Guerrero, Pedro M García López, Ana E González Santiago, José A Domínguez Rosales, Carmen M Gurrola Díaz
Format:	Article
Language:	English
Published:	BMC 2013-01-01
Series:	Biological Research
Subjects:	chronic hyperglycemia in vivo diabetes models lns-1 gene type 2 diabetes
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000300009&lng=en&tlng=en

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