Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies

Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies

Summary: The relevance of topographic cues for commitment of induced pluripotent stem cells (iPSCs) is largely unknown. In this study, we demonstrate that groove-ridge structures with a periodicity in the submicrometer range induce elongation of iPSC colonies, guide the orientation of apical actin f...

Full description

Bibliographic Details
Main Authors: Giulio Abagnale, Antonio Sechi, Michael Steger, Qihui Zhou, Chao-Chung Kuo, Gülcan Aydin, Carmen Schalla, Gerhard Müller-Newen, Martin Zenke, Ivan G. Costa, Patrick van Rijn, Arnold Gillner, Wolfgang Wagner
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117302795

Internet

http://www.sciencedirect.com/science/article/pii/S2213671117302795

Similar Items