Cytotoxicity and genotoxicity of bioceramic root canal sealers compared to conventional resin-based sealer

Abstract The aim of this study was to evaluate cytotoxicity and genotoxicity of calcium-silicate based sealers and comparing them with a gold standard—an epoxy-based sealant. Two experimental cell lines were used, gingival fibroblasts (hGF) and monocyte/macrophage peripheral blood cell line (SC). Th...

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Bibliographic Details
Main Authors: Mateusz Radwanski, Wioletta Rozpedek-Kaminska, Grzegorz Galita, Natalia Siwecka, Jerzy Sokolowski, Ireneusz Majsterek, Mutlu Özcan, Monika Lukomska-Szymanska
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-54726-1