Mechanism of calcitonin gene related peptide against acute pancreatitis in rats by modulating amino acid metabolism based on metabonomics

Abstract To study the mechanism of calcitonin gene related peptide(CGRP) protecting acute pancreatitis based on metabolomics. 24 adult male rats were randomly divided into control group (Con), acute pancreatitis model group (AP), CGRP treatment group (CGRP + AP, abbreviated as CGRP) and CGRP antagon...

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Bibliographic Details
Main Authors: Jian-Xiong Hu, Ying-Kai Chen, Shi-Jun Chen, Yan-Ya Lin, Jun-Nian Chen, Ying Xie, Cheng-Fei Zhao, Cun-Rong Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-87707-z