Antioxidant and Cytotoxic Activity of New Polyphenolic Derivatives of Quinazolin-4(3H)-one: Synthesis and In Vitro Activities Evaluation

Antioxidant and Cytotoxic Activity of New Polyphenolic Derivatives of Quinazolin-4(3H)-one: Synthesis and In Vitro Activities Evaluation

The development of hybrid molecules with significant human therapeutic properties is one of the main approaches of pharmaceutical research. One of the most important pharmacophores is the quinazolin-4(3H)-one heterocycle moiety, due to its wide range of biological activities. By its derivatization w...

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Bibliographic Details
Main Authors: Raluca Pele, Gabriel Marc, Ioana Ionuț, Cristina Nastasă, Ionel Fizeșan, Adrian Pîrnău, Laurian Vlase, Mariana Palage, Smaranda Oniga, Ovidiu Oniga
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
quinazolin-4(3H)-one
phenolic derivatives
hybrid molecules
in vitro evaluation
antioxidant
cytotoxic
Online Access:https://www.mdpi.com/1999-4923/15/1/136

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https://www.mdpi.com/1999-4923/15/1/136

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