Metabolic approaches to rescue antitumor Vγ9Vδ2 T-cell functions in myeloma
Vγ9Vδ2 T cells are immune effector cells very well-suited for immunotherapy, but clinical results have been disappointing in multiple myeloma (MM) and other cancers. We have shown that Vγ9Vδ2 T cells are victimized prematurely by the immune suppressive tumor microenvironment (TME) established by mye...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
IMR Press
2020-01-01
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Series: | Frontiers in Bioscience-Landmark |
Subjects: | |
Online Access: | https://www.imrpress.com/journal/FBL/25/1/10.2741/4795 |