Immunothrombosis and Complement Activation Contribute to Disease Severity and Adverse Outcome in COVID-19

Immunothrombosis and Complement Activation Contribute to Disease Severity and Adverse Outcome in COVID-19

Severe COVID-19 is characterized by systemic inflammation and multiple organ dysfunction syndrome (MODS). Arterial and venous thrombosis are involved in the pathogenesis of MODS and fatality in COVID-19. There is evidence that complement and neutrophil activation in the form of neutrophil extracellu...

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Bibliographic Details
Main Authors: Tiphaine Ruggeri, Yasmin De Wit, Noëlia Schärz, Gerard van Mierlo, Anne Angelillo-Scherrer, Justine Brodard, Joerg C. Schefold, Cédric Hirzel, Ilse Jongerius, Sacha Zeerleder
Format: Article
Language:English
Published: Karger Publishers 2023-11-01
Series:Journal of Innate Immunity
Subjects:
thrombosis
cell-free dna
complement activation
covid-19
neutrophil activation
Online Access:https://beta.karger.com/Article/FullText/533339

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https://beta.karger.com/Article/FullText/533339

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