Mitochondrial adaptation in cancer drug resistance: prevalence, mechanisms, and management

Abstract Drug resistance represents a major obstacle in cancer management, and the mechanisms underlying stress adaptation of cancer cells in response to therapy-induced hostile environment are largely unknown. As the central organelle for cellular energy supply, mitochondria can rapidly undergo dyn...

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Bibliographic Details
Main Authors: Ping Jin, Jingwen Jiang, Li Zhou, Zhao Huang, Edouard C. Nice, Canhua Huang, Li Fu
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-022-01313-4