Ecological effects of cefepime use during antibiotic cycling on the Gram-negative enteric flora of ICU patients

Abstract This study examines the impact of cefepime and APP-β (antipseudomonal penicillin/ β-lactamase inhibitor combinations) on Gram-negative bacterial colonization and resistance in two Australian ICUs. While resistance did not cumulatively increase, cefepime (but not APP-β treatment) was associa...

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Bibliographic Details
Main Authors: Carola Venturini, Andrew N. Ginn, Brooke E. Wilson, Guy Tsafnat, Ian Paulsen, Sally R. Partridge, Jonathan R. Iredell
Format: Article
Language:English
Published: SpringerOpen 2018-07-01
Series:Intensive Care Medicine Experimental
Online Access:http://link.springer.com/article/10.1186/s40635-018-0185-2