A Limited Role for the Cell Cycle Regulator Cyclin A1 in Murine Leukemogenesis.

The quest for novel therapeutic targets in acute myeloid leukemia (AML) is still ongoing. One of such targets, cyclin A1, was shown to be overexpressed in AML including AML stem cells. However, the function of cyclin A1 in AML is largely unknown, and the data on its impact on patients' survival...

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Bibliographic Details
Main Authors: Nicole Bäumer, Sebastian Bäumer, Miriam Haak, Steffen Koschmieder, Kai Schönig, Wolfgang E Berdel, Carsten Müller-Tidow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4469679?pdf=render