YIV-906 potentiated anti-PD1 action against hepatocellular carcinoma by enhancing adaptive and innate immunity in the tumor microenvironment

YIV-906 potentiated anti-PD1 action against hepatocellular carcinoma by enhancing adaptive and innate immunity in the tumor microenvironment

Abstract YIV-906 (PHY906) is a standardized botanical cancer drug candidate developed with a systems biology approach—inspired by a traditional Chinese herbal formulation, historically used to treat gastrointestinal symptoms including diarrhea, nausea and vomiting. In combination with chemotherapy a...

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Bibliographic Details
Main Authors: Xiaochen Yang, Wing Lam, Zaoli Jiang, Fulan Guan, Xue Han, Rong Hu, Wei Cai, William Cheng, Shwu-Huey Liu, Peikwen Cheng, Yuping Cai, Nicholas J. W. Rattray, Caroline H. Johnson, Lieping Chen, Yung-Chi Cheng
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91623-3

Internet

https://doi.org/10.1038/s41598-021-91623-3

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