Increased Risk of Interstitial Lung Disease in Children with a Single R288K Variant of ABCA3
Abstract The ABCA3 gene encodes a lipid transporter in type II pneumocytes critical for survival and normal respiratory function. The frequent ABCA3 variant R288K increases the risk for neonatal respiratory distress syndrome among term and late preterm neonates, but its role in children’s interstiti...
Main Authors: | , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2016-02-01
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Series: | Molecular Medicine |
Online Access: | http://link.springer.com/article/10.2119/molmed.2015.00244 |