Oropouche Virus Infects, Persists and Induces IFN Response in Human Peripheral Blood Mononuclear Cells as Identified by RNA PrimeFlow™ and qRT-PCR Assays

Oropouche Virus Infects, Persists and Induces IFN Response in Human Peripheral Blood Mononuclear Cells as Identified by RNA PrimeFlow™ and qRT-PCR Assays

<i>Oropouche orthobunyavirus</i> (OROV) is an emerging arbovirus with a high potential of dissemination in America. Little is known about the role of peripheral blood mononuclear cells (PBMC) response during OROV infection in humans. Thus, to evaluate human leukocytes susceptibility, per...

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Bibliographic Details
Main Authors: Mariene Ribeiro Amorim, Marjorie Cornejo Pontelli, Gabriela Fabiano de Souza, Stéfanie Primon Muraro, Daniel A. Toledo-Teixeira, Julia Forato, Karina Bispo-dos-Santos, Natália S. Barbosa, Matheus Cavalheiro Martini, Pierina Lorencini Parise, Aline Vieira, Guilherme Paier Milanez, Luis Lamberti Pinto daSilva, Pritesh Jaychand Lalwani, Alessandro Santos Farias, Marco Aurélio Ramirez Vinolo, Renata Sesti-Costa, Eurico Arruda, Jose Luiz Proenca-Modena
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
Oropouche virus
PBMC
lymphocyte
interferons
RNA PrimeFlow™
dendritic cells
Online Access:https://www.mdpi.com/1999-4915/12/7/785

Internet

https://www.mdpi.com/1999-4915/12/7/785

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