Subordinate Effect of -21M HLA-B Dimorphism on NK Cell Repertoire Diversity and Function in HIV-1 Infected Individuals of African Origin

Natural Killer (NK) cells play an important role in antiviral defense and their potent effector function identifies them as key candidates for immunotherapeutic interventions in chronic viral infections. Their remarkable functional agility is achieved by virtue of a wide array of germline-encoded in...

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Hlavní autoři: Elia Moreno Cubero, Ane Ogbe, Isabela Pedroza-Pacheco, Myron S. Cohen, Barton F. Haynes, Persephone Borrow, Dimitra Peppa
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2020-02-01
Edice:Frontiers in Immunology
Témata:
On-line přístup:https://www.frontiersin.org/article/10.3389/fimmu.2020.00156/full