Mannan-binding lectin suppresses growth of hepatocellular carcinoma by regulating hepatic stellate cell activation via the ERK/COX-2/PGE2 pathway

Mannan-binding lectin suppresses growth of hepatocellular carcinoma by regulating hepatic stellate cell activation via the ERK/COX-2/PGE2 pathway

Mannan binding lectin (MBL), initially known to activate the complement lectin pathway and defend against infection, was recently shown to be potentially involved in the development of several types of cancer; however, its exact role in cancers, especially its effect on tumor microenvironment remain...

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Bibliographic Details
Main Authors: Junru Li, Huifang Li, Yu Yu, Yan Liu, Yunzhi Liu, Qiang Ma, Liyun Zhang, Xiao Lu, Xiang-yang Wang, Zhengliang Chen, Daming Zuo, Jia Zhou
Format: Article
Language:English
Published: Taylor & Francis Group 2019-02-01
Series:OncoImmunology
Subjects:
mannan binding lectin
hepatocellular carcinoma
hepatic stellate cells
erk/cox-2/pge2 pathway
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1527650

Internet

http://dx.doi.org/10.1080/2162402X.2018.1527650

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