Spontaneous Formation of Melanin from Dopamine in the Presence of Iron

Spontaneous Formation of Melanin from Dopamine in the Presence of Iron

Parkinson’s disease is associated with degeneration of neuromelanin (NM)-containing substantia nigra dopamine (DA) neurons and subsequent decreases in striatal DA transmission. Dopamine spontaneously forms a melanin through a process called melanogenesis. The present study examines conditions that p...

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Bibliographic Details
Main Authors: David M. Hedges, Jordan T. Yorgason, Andrew W. Perez, Nathan D. Schilaty, Benjamin M. Williams, Richard K. Watt, Scott C. Steffensen
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Antioxidants
Subjects:
dopamine
melanin
neuromelanin
oxidative stress
iron
Online Access:https://www.mdpi.com/2076-3921/9/12/1285

Internet

https://www.mdpi.com/2076-3921/9/12/1285

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