Malaria severity: Possible influence of the E670G PCSK9 polymorphism: A preliminary case-control study in Malian children.

Malaria severity: Possible influence of the E670G PCSK9 polymorphism: A preliminary case-control study in Malian children.

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a hepatic secretory protein which promotes the degradation of low-density lipoprotein receptors leading to reduced hepatic uptake of plasma cholesterol. Non-synonymous single-nucleotide polymorphisms in its gene have been linked to hypo- or hy...

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Bibliographic Details
Main Authors: Charles Arama, Issa Diarra, Bourèma Kouriba, Francine Sirois, Olesya Fedoryak, Mahamadou A Thera, Drissa Coulibaly, Kirsten E Lyke, Christopher V Plowe, Michel Chrétien, Ogobara K Doumbo, Majambu Mbikay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5813955?pdf=render

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http://europepmc.org/articles/PMC5813955?pdf=render

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