A human leukocyte antigen imputation study uncovers possible genetic interplay between gut inflammatory processes and autism spectrum disorders

A human leukocyte antigen imputation study uncovers possible genetic interplay between gut inflammatory processes and autism spectrum disorders

Abstract Autism spectrum disorders (ASD) are neurodevelopmental conditions that are for subsets of individuals, underpinned by dysregulated immune processes, including inflammation, autoimmunity, and dysbiosis. Consequently, the major histocompatibility complex (MHC)-hosted human leukocyte antigen (...

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Bibliographic Details
Main Authors: Laura Lombardi, Sigrid Le Clerc, Ching-Lien Wu, Jihène Bouassida, Wahid Boukouaci, Sobika Sugusabesan, Jean-Romain Richard, Mohamed Lajnef, Maxime Tison, Philippe Le Corvoisier, Caroline Barau, Tobias Banaschewski, Rosemary Holt, Sarah Durston, Antonio M. Persico, Bethany Oakley, Eva Loth, Jan Buitelaar, Declan Murphy, Marion Leboyer, Jean-François Zagury, Ryad Tamouza
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02550-y

Internet

https://doi.org/10.1038/s41398-023-02550-y

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