Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

<p>Abstract</p> <p>Background</p> <p>The form(s) of amyloid-β peptide (Aβ) associated with the pathology characteristic of Alzheimer's disease (AD) remains unclear. In particular, the neurotoxicity of intraneuronal Aβ accumulation is an issue of considerable contro...

Full description

Bibliographic Details
Main Authors: Youmans Katherine L, Tai Leon M, Kanekiyo Takahisa, Stine W Blaine, Michon Sara-Claude, Nwabuisi-Heath Evelyn, Manelli Arlene M, Fu Yifan, Riordan Sean, Eimer William A, Binder Lester, Bu Guojun, Yu Chunjiang, Hartley Dean M, LaDu Mary Jo
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Molecular Neurodegeneration
Subjects:
Intraneuronal
Aβ
APP
MOAB-2
3xTg
5xFAD
Antibody
Alzheimer's disease
Online Access:http://www.molecularneurodegeneration.com/content/7/1/8

Internet

http://www.molecularneurodegeneration.com/content/7/1/8

Similar Items