Characterization of the Native Disulfide Isomers of the Novel χ-Conotoxin PnID: Implications for Further Increasing Conotoxin Diversity

Characterization of the Native Disulfide Isomers of the Novel χ-Conotoxin PnID: Implications for Further Increasing Conotoxin Diversity

χ-Conotoxins are known for their ability to selectively inhibit norepinephrine transporters, an ability that makes them potential leads for treating various neurological disorders, including neuropathic pain. PnID, a peptide isolated from the venom of <i>Conus pennaceus</i>, shares high...

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Bibliographic Details
Main Authors: Michael J. Espiritu, Jonathan K. Taylor, Christopher K. Sugai, Parashar Thapa, Nikolaus M. Loening, Emma Gusman, Zenaida G. Baoanan, Michael H. Baumann, Jon-Paul Bingham
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Marine Drugs
Subjects:
peptide
toxins
conotoxins
isomers
structure
monoamine transporters
Online Access:https://www.mdpi.com/1660-3397/21/2/61

Internet

https://www.mdpi.com/1660-3397/21/2/61

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