Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels

Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels

Iron is an essential metal for cellular metabolism and signaling, but it has adverse effects in excess. The physiological consequences of iron deficiency are well established, yet the relationship between iron supplementation and pericellular oxygen levels in cultured cells and their downstream effe...

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Bibliographic Details
Main Authors: Gulsah Sevimli, Matthew J. Smith, Tuba Akgul Caglar, Şükriye Bilir, Melike Secilmis, Hamza Y. Altun, Esra N. Yigit, Fan Yang, Thomas P. Keeley, Roland Malli, Gürkan Öztürk, Giovanni E. Mann, Emrah Eroglu
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Redox Biology
Subjects:
Pericellular oxygen
Hyperoxia
Normoxia
NO bioavailability
geNOps
Ferrous iron
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172200091X

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http://www.sciencedirect.com/science/article/pii/S221323172200091X

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