The role of retroelements in the development of hereditary tumor syndromes
Genomic instability caused by activated retroelements plays an important role in the development of malignant neoplasms. Activated retroelements cause enhanced expression of oncogenes containing transposon sequences in their promoters and introns. Oncosuppressor genes contain hot spots of insertiona...
Main Authors: | , |
---|---|
Format: | Article |
Language: | Russian |
Published: |
ABV-press
2021-12-01
|
Series: | Успехи молекулярной онкологии |
Subjects: | |
Online Access: | https://umo.abvpress.ru/jour/article/view/388 |