Depletion of regulatory T cells enhancing the anti-tumor effect of in situ vaccination in solid tumors

The emergence of immune checkpoint inhibitors (ICIs) has revolutionized the clinical treatment for tumor. However, the low response rate of ICIs remains the major obstacle for curing patients and effective approaches for patients with primary or secondary resistance to ICIs remain lacking. In this s...

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Bibliographic Details
Main Authors: Ya-Jia Xie, Sha Tian, Min Huang, Lin-Lin Lu, Zhong-Qiu Liu, Jun-Hui Chen, Xing-Xing Fan
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Pharmacological Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S104366182400118X