Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis

Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis

<p>Abstract</p> <p>Background</p> <p>We have recently identified HOP hoemobox (HOPX) as a tumor suppressor gene candidate, characterized by tumor-specific promoter DNA hypermethylation in human cancers, and it can remarkably inhibit tumors’ aggressive phenotypes. In thi...

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Bibliographic Details
Main Authors: Waraya Mina, Yamashita Keishi, Katoh Hiroshi, Ooki Akira, Kawamata Hiroshi, Nishimiya Hiroshi, Nakamura Kazunori, Ema Akira, Watanabe Masahiko
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Cancer
Subjects:
HOP homeobox
Pancreatic cancer
Methylation
Online Access:http://www.biomedcentral.com/1471-2407/12/397

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http://www.biomedcentral.com/1471-2407/12/397

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