Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis
<p>Abstract</p> <p>Background</p> <p>We have recently identified HOP hoemobox (HOPX) as a tumor suppressor gene candidate, characterized by tumor-specific promoter DNA hypermethylation in human cancers, and it can remarkably inhibit tumors’ aggressive phenotypes. In thi...
Main Authors: | Waraya Mina, Yamashita Keishi, Katoh Hiroshi, Ooki Akira, Kawamata Hiroshi, Nishimiya Hiroshi, Nakamura Kazunori, Ema Akira, Watanabe Masahiko |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-09-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2407/12/397 |
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