The Basis and Advances in Clinical Application of Cytomegalovirus-Specific Cytotoxic T Cell Immunotherapy for Glioblastoma Multiforme

The Basis and Advances in Clinical Application of Cytomegalovirus-Specific Cytotoxic T Cell Immunotherapy for Glioblastoma Multiforme

A high percentage of malignant gliomas are infected by human cytomegalovirus (HCMV), and the endogenous expression of HCMV genes and their products are found in these tumors. HCMV antigen expression and its implications in gliomagenesis have emerged as a promising target for adoptive cellular immuno...

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Bibliographic Details
Main Authors: Amin Daei Sorkhabi, Aila Sarkesh, Hossein Saeedi, Faroogh Marofi, Mahnaz Ghaebi, Nicola Silvestris, Behzad Baradaran, Oronzo Brunetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
immunotherapy
adoptive cellular therapy (ACT)
CMV-specific T cell
cytomegalovirus (CMV)
herpes virus
glioblastoma multiforme
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.818447/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.818447/full

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