Temporal dynamics of TNF-mediated changes in hematopoietic stem cell function and recovery

Summary: While tumor necrosis factor (TNF) is a critical mediator of appropriate immune response and tissue repair, its misregulation is linked to cancer, autoimmunity, bone marrow failure, and aging. Understanding the context-dependent roles of TNF is essential for elucidating normal and pathogenic...

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Bibliographic Details
Main Authors: Alexandra Rundberg Nilsson, Isabel Hidalgo, David Bryder, Cornelis Jan Pronk
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223004182