Comparison of Fc N-Glycosylation of Pharmaceutical Products of Intravenous Immunoglobulin G.

Intravenous immunoglobulin (IVIg) products from different pharmaceutical companies vary in composition, in part because of the selected blood donors and production process. N-glycosylation of the Fc-portion of IgG varies between blood donors and may influence both the side-effects and therapeutic ef...

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Bibliographic Details
Main Authors: Willem Jan R Fokkink, David Falck, Tom C M Santbergen, Ruth Huizinga, Manfred Wuhrer, Bart C Jacobs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4601728?pdf=render