Glucose Concentration in Regulating Induced Pluripotent Stem Cells Differentiation Toward Insulin-Producing Cells

Glucose Concentration in Regulating Induced Pluripotent Stem Cells Differentiation Toward Insulin-Producing Cells

The generation of insulin-producing cells from human-induced pluripotent stem cells holds great potential for diabetes modeling and treatment. However, existing protocols typically involve incubating cells with un-physiologically high concentrations of glucose, which often fail to generate fully fun...

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Bibliographic Details
Main Authors: Chencheng Wang, Shadab Abadpour, Petter Angell Olsen, Daxin Wang, Justyna Stokowiec, Simona Chera, Luiza Ghila, Helge Ræder, Stefan Krauss, Aleksandra Aizenshtadt, Hanne Scholz
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Transplant International
Subjects:
stem cell-derived beta cells
mitochondria
glucose
stem cell differentiation
induced pluripotent stem cells
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2024.11900/full

Internet

https://www.frontierspartnerships.org/articles/10.3389/ti.2024.11900/full

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