Double-Negative T-Cells during Acute Human Immunodeficiency Virus and Simian Immunodeficiency Virus Infections and Following Early Antiretroviral Therapy Initiation

Double-Negative T-Cells during Acute Human Immunodeficiency Virus and Simian Immunodeficiency Virus Infections and Following Early Antiretroviral Therapy Initiation

HIV infection significantly affects the frequencies and functions of immunoregulatory CD3<sup>+</sup>CD4<sup>−</sup>CD8<sup>−</sup> double-negative (DN) T-cells, while the effect of early antiretroviral therapy (ART) initiation on these cells remains understudied....

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Bibliographic Details
Main Authors: Alexis Yero, Tao Shi, Julien A. Clain, Ouafa Zghidi-Abouzid, Gina Racine, Cecilia T. Costiniuk, Jean-Pierre Routy, Jérôme Estaquier, Mohammad-Ali Jenabian
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Viruses
Subjects:
CD4<sup>−</sup>CD8<sup>−</sup> T-cells
double negative (DN) T-cells
acute SIV infection
acute HIV infection
early ART
regulatory T-cells (Tregs)
Online Access:https://www.mdpi.com/1999-4915/16/10/1609

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https://www.mdpi.com/1999-4915/16/10/1609

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